Biochemistry and Biophysics Seminars

Innovating Antimicrobial Strategies Through Structural Biology

Engineering genetically encoded fluorescent sensors to reveal zinc signaling in live cells

Chaperones Play Hot Potato with Unfolded Proteins in the Periplasm Cancelled

Mitochondria as signaling organelles control physiology and disease

Measuring Biomolecular Structure and Interactions using Hyperpolarized Ligands 

Shoot control of root growth under light-limiting conditions at a cellular resolution in Arabidopsis

Phage-host dynamics at the microscale in bacterial biofilm communities 

Deconstructing the complexity of polyclonal antibody responses at the molecular level using cryoEM. 

Single-Molecule Visualization and Manipulation of Protein-DNA Interactions

Genome maintenance at higher resolution

Cancelled-Mechanistic insight into α-synuclein aggregation processes in neurodegenerative disease

Telomere Maintenance in Trypanosoma brucei 

Neurobiology Discovery through Systems Biology of a Rare Genetic Disorder

Mechanisms of pathogenesis for Clostridioides difficile toxins 

Breaking the Cycle: Targeting Insect Tyrosine Metabolism to Halt Malaria and NTD Transmission 

Protein folding elements drive genetic innovation in antibiotic resistance genes

Brain-Derived Tau Aggregated Polymorphs: Characterization and Biological Activity

Rewiring the immune response through biomolecular engineering

Bacterial cell division: how the Z ring leads to activation of septal peptidoglycan synthesis

Recent insights into membrane tubulation in endosomes and autolysosomes.

The Distinct Roles of Copper Transporters ATP7A and ATP7B in Mammalian Cell Physiology

It takes two to tango: Transporter-Kinase Complexes for Antimicrobial Peptide Resistance

New Strategies for Stereoselective Radical Biocatalysis

Metabolism: The clock of the eukaryotic cell?

The velocity of life — investigating the temporal dynamics of molecules, cells and organisms by single-cell genomics

Novel Dual NR4A1/NR4A2 ligands Inhibit Tumor Growth and Reverse T Cell Exhaustion

Engineering locally delivered protein therapeutics

The dynamic nature of G protein-coupled receptor (GPCR) allostery and signaling bias

Uncovering the cell biology of viral infection through genome-scale genetic screens

Evidence of a catalytic dyad withing F420-dependent glucose-6-phosphate dehydrogenase

On the Origin of Asymmetry in the Tautomerase Superfamily

Engineered Biomaterials for Regenerative Medicine, Drug Delivery and 3D Bioprinting

Structural characterization of biological systems at macro and nanoscale using vibrational spectroscopy

Metals and Membranes in Mitochondrial Metabolism and Human Disease

Single-Cell Studies of Phage Infection and Implications on Antibacterial Strategies

Regulation of lipid signaling by peripheral membrane proteins: A trilogy

Suppressing Suppression: A myeloid centric approach to immune sensitization of the breast cancer microenvironment

Cryogenic electron imaging of biomolecules and cells beyond expectations.

The bacterial sense of touch: how single cells distinguish soft from firm using molecular-scale fingers

The Genetic Landscape of a Metanbolic Interaction

OAT1 is a universal metabolite repair enzyme that removes a strong inhibitor of the TCA cycle

Orchestrating Aging across a troubled soma; insights into the molecular basis of aging

SAGA Functions in Development and Disease

Conformational disorder in regulation of enzymatic catalysis

Nanodiscs for Revealing the Structure and Function of Membrane Proteins

Mechanisms of RNA Polymerase II Transcription

Higher order oligomerization of KicGAS is essential for DNA-induced phase separation and cGAS inhibition

A Basic Science CRO: Molecular Cell Mechanisms of an Iron Chelator in Clinical Trials for Multiple System Atrophy

Dynamic evolution of gene duplications in shaping trait variation in nature and agriculture