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Sui, Xuewu

Xuewu Sui

Assistant Professor
Focus Area:  Lipid biology, lipid biosynthesis and regulation, membranes, neutral lipids, phospholipids, drug discovery and development, molecular pharmacology, cryo-electron microscopy, crystallography
Office:  
BCBP 418A
Email:  
Phone:  
979-314-8283

Education

Undergraduate Education
B.S. Nanjing Agricultural University, Nanjing, China (2008)
Graduate Education
M.S. Nankai University, Tianjin, China (2011)
Ph.D. Case Western Reserve University (2016)
Postdoctoral Training: Department of Cell Biology, Harvard Medical School
Postdoctoral Training: Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health

Areas of Expertise

  • Biochemistry
  • Single Particle cryo-EM and X-ray Crystallography
  • Pharmacology
  • Lipid Biology

Professional Summary

Lipids play crucial roles in a diverse array of biological processes. Unlike soluble nutrients (e.g., amino acids and sugars), lipid molecules are primarily hydrophobic. Their biosynthesis and metabolism occur predominantly at membranes and are facilitated by membrane proteins. We employ multidisciplinary approaches including biochemistry, biophysics, and structural biology to answer how lipid are metabolized at the molecular level. In addition, we also employ genetic and cell imaging methods trying to identify novel factors that govern lipid metabolic pathways. Our overarching goal of our research program is to enhance our comprehension of lipid biology and contribute to the advancement of therapeutic strategies for lipid-related disorders

Publications