Cryo-electron microscopy resource for studying life at the molecular level
![Titan Krios cryo-electron microscopy](https://bcbp.tamu.edu/wp-content/uploads/2022/05/Cryo-electron-microscopy-768x1024.jpg)
![May 17, 2022: Installation of the Krios has begun, starting with the acoustic cage. Photo courtesy of Gaya Yadav](https://bcbp.tamu.edu/wp-content/uploads/2022/05/20220516_172901m-768x1024.jpg)
![May 31, 2022: The acoustic enclosure for the microscope has been completed. Image courtesy of Gaya Yadav](https://bcbp.tamu.edu/wp-content/uploads/2022/06/20220527_090637-768x1024.jpg)
![May 31, 2022: For Cryo-EM sample prep, the Dual Chamber EasiGlow System. Ionized air during the glow discharge process glows pink. Image courtesy of Gaya Yadav](https://bcbp.tamu.edu/wp-content/uploads/2022/06/20220527_121835-scaled-e1654191737930.jpg)
![man on ladder behind an instrument](https://bcbp.tamu.edu/wp-content/uploads/2022/07/FSE_connecting-HT-Tank-768x863.jpg)
![complex wiring and instrumentation](https://bcbp.tamu.edu/wp-content/uploads/2022/07/TitanKrios_internal-768x1024.jpg)
![June 29, 2022: The outer look of Thermo Scientific Krios G4 Cryo Transmission Electron Microscope](https://bcbp.tamu.edu/wp-content/uploads/2022/07/TitanKrios-768x1259.jpg)
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Soon, the Department of Biochemistry and Biophysics at Texas A&M University will house a leading-edge 300 kV cryo-electron microscope.
The instrument is an award-winning Krios G4, which provides never-before-achieved atomic resolution for single particle and tomographic cryo-electron microscopy, cryo-EM.
The precisely renovated room for the instrument in the Biochemistry and Biophysics Building has recently passed inspection. Now, technical experts from Thermo-Fisher are installing the instrument in collaboration with Gaya Yadav, Ph.D., technical director of the cryo-EM resource; Terry Lovingshimer, Operations Manager for Biochemistry and Biophysics; and Junjie Zhang, Ph.D., Associate Professor and faculty director for the resource.
“This represents a leap forward and a remarkable new capability at Texas A&M,” said Josh Wand, Ph.D., University Distinguished Professor and Head of the Department of Biochemistry and Biophysics. “Our department is leading this effort. This instrumentation will enable ground-breaking research and will be a platform for future recruitments.”
The facility is expected to be open by late summer or early fall 2022 to support research within The Texas A&M University System and beyond.
To learn more, contact Dr. Gaya Yadav at [email protected].